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Materials and methods Animals Four-week-old male ICR mice (20-22 g) (Daehan Bio Link, Eumseong, Korea) were acclimatized for one week in the normal conditions of the laboratory

So free radicals, heavy metals, and environmental toxins stick to it

The channel was firstly expressed in rats through activation of high temperature and pungent hot chili pepper component (capsaicin) in mice DRG neuron (Caterina et al., 2006)