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10.3389/fped.2022.866295 [DOI] [PMC free article] [PubMed] [Google Scholar] Henrik K., Isaksson F., Juul A., Rasmussen M

In summary, MAT, Dabrafenib, bone marrow mesenchymal stem cell-derived exosomes miR-367-3p, and DFP modulate ferroptosis, iron deposition, lipid peroxidation, neuroinflammation, microglial activation, and myelin loss, thereby attenuating MS-related pathological damage

Aged BM-MSCs exhibit reduced differentiation and proliferation alongside increased senescence, processes mediated by HDACs and longevity-related deacetylases such as sirtuins (SIRT)