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doi: 10.1007/s10741-021-10199-2 Summary Keywords clinical translation, drug delivery, mitochondrial dysfunction, mitophagy, osteoarthritis, oxidative stress, targeted therapy Citation Zhang S-O, Gu Z-Q, Ruan J, Zhang J and Chen H (2026) Mitochondrial-targeted therapy for osteoarthritis: Challenges and opportunities from basic research to clinical translation

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In trained monocytes, elevated NAD + /NADH ratios and lactate accumulation modulate HDAC activity and influence downstream gene expression (167, 168)

Oxidative stress status of highly prolific sows during gestation and lactation