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This prospective phase II trial evaluated FTD/TPI plus ramucirumab in heavily pretreated gastric cancer, including older patients and those with ECOG PS 0-2, aiming to better reflect routine clinical practice

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In particular, the vitamin can reduce the production of prostaglandin E2, which helps to regulate inflammatory pathways [40]

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Figure 21: Blackboard from EMBO course showing Dutton's experimental protocol for in vitro immune response, 1967 (credit: Lefkovits, Waldmann, 1979)