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Many senolytic drugs are already approved for human use and many cells expressing senescence have been identified in other types of chronic kidney disease, however these studies did not include patients with lupus

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Another large cohort study of patients treated with TNF alpha inhibitors 6 also found an increased incidence of bacterial skin infections, as well as a high incidence of herpes virus skin infections

Its a rule of thumb, not a law of physics there are exceptions but as a first-pass filter for will this absorb from the gut, it holds up well