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Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cells

Specifically, we found that PANC-1 cells had relatively higher levels of GSTM3 expression, whereas MIA PaCa-2 cells had relatively lower levels (Figure 2A)

This suggestion was further insisted as a potential mechanism of TB-500 by the authors of the research study, who also commented that " transfection of anti-miR-146a nucleotides reversed the inhibitory effect of T4 on IRAK1 and TRAF6

Welmer A-K Journal article: AGING CLINICAL AND EXPERIMENTAL RESEARCH

doi: 10.1021/acsnano.3c08174 111 MuMWangGChenBLiHFengCFanRet al