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10.1007/s00604-022-05570-5 49 MohammadniaeiM.KoyappayilA.SunY.MinJ.LeeM

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A randomized double-blind controlled trial revealed that synbiotic supplementation increased the F/B ratio in the gut microbiota of SLE patients, promoted butyrate metabolism, reduced IL-6 levels and systemic inflammation, thereby improving SLEDAI scores [94]