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PloS One (2011) 6:e22485

At the time, the FDA presented a lot of adverse event data that showed there was a risk of immunogenicity immune reactions and that raised some red flags for the committee, said Gupta, an adjunct assistant professor of anesthesiology at the Johns Hopkins University School of Medicine

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The GSDMD inhibitor Disulfiram (DSF) can inhibit the release of NETs (113), suggesting that different forms of neutrophil death are interconnected and collectively affect the body's immune function