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Vitamin C Enhances glutathione levels and provides additional antioxidant protection

That can affect tissues, proteins, cell membranes, and DNA

The mechanism of this VEGF-independence is not clear

However, in Vitis flexuosa different GTSs may play diverse roles in pathogen defense, since only one out of five characterized GST genes was induced, while expression of the other GSTs was down-regulated following infection by the necrotrophic fungi B