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Thrombolysis remains a major strategy for the treatment of ischemic stroke

Fredman G, Ozcan L, Spolitu S, Hellmann J, Spite M, Backs J, et al

In addition, the combination of Exos with antioxidants, iron chelators, or other therapeutic agents could boost their efficacy

To purify FBU-His-EEHV-EE2, cell pellets were incubated in lysis buffer (20 mM Tris-HCl, pH 7.8, 0.5 M NaCl, 10 mM imidazole, 6 M guanidine hydrochloride (GdmCl)) for 15 min on ice