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2019 Oct;18(5):28-35

Regarding the effects of doxycycline on gut microbiota, previous studies have noticed an effect of this antibiotic on a short-term reduction of LAB like Bifidobacterium or Lactobacillus [325, 326]

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Furthermore, by blocking the PI3K/Akt/mTOR signaling pathway, deltonin could also reduce the expression levels of important DNA-repair enzymes, such as Rad51 and murine double minute (MDM)2 (155)