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The 24-week trial is the longest controlled human study

Retatrutide is administered once weekly, while GLOW is administered daily

While their primary use has been in anti-aging and muscle-building circles, increased GH can also lead to reduced body fat and increased lean muscle mass , making these peptides attractive for weight management

Additionally, downregulation of nuclear factor erythroid 2-related factor 2 (Nrf2), a crucial regulator of the cellular antioxidant response, compromises the hepatocytes first-line defence against oxidative injury [50, 51]