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[DOI] [PMC free article] [PubMed] [Google Scholar] 172.Patel D, Gupta S

Moreover, malate metabolism by this enzyme plays a key role in interconversion of carbon residues in contributing biosynthetic pools of metabolites [71]

Experiments performed on isolated rat liver mitochondria, cultured intact cells (astrocytes, HEK 293) and rabbit cardiomyocytes demonstrated that levels of polyP were increased by substrates of the mitochondrial respiratory chain and in turn reduced by mitochondrial inhibitor (rotenone) or respiratory chain uncouplers [carbonylcyanide p -trifluoromethoxyphenylhydrazone (FCCP) or carbonylcyanide-m-chlorophenylhydrazone (CCCP)]