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In terms of functional specificity, quercetin mitigates fibrosis progression in diabetic nephropathy and chronic kidney disease by inhibiting the TGF-/Smad signaling pathway (Aghababaei and Hadidi, 2023), whereas kaempferol regulates bile acid metabolism, promotes cholesterol efflux, and suppresses foam cell formation, thereby alleviating conditions such as NAFLD, NASH, and hypercholesterolemia (Yao et al., 2024)