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Our scRNA-seq data indicated that GSH metabolism score was significantly lower in Mac-CF MDM than in Ctrl MDM at Day 3 post-challenge, and scores for GSH peroxidase and GSH transferase were significantly lower in Mac-CF MDM at Day 3 and 5 post-inoculation ( Figures 6AC )

In short, a solution of 50% isopropanol, 6% TFA, and 1 mM monopotassium phosphate (KH2PO4) was added to the digested lysate

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Patients may achieve additional weight loss, typically around 5-10% of their body weight, though results vary considerably between individuals