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BPC-157 directs the repair process, accelerating the healing of tendons, ligaments, muscles, and even the gut lining

it was initially studied as an antidepressant before Phase 2 trials identified significant weight loss as a secondary outcome

This increases cost without clear benefit and eliminates the ability to increase dose if initial response is insufficient

A systematic review published in 2025 identified 544 total articles on BPC-157 published between 1993 and 2024, filtering to 36 studies meeting inclusion criteria

However, the aforementioned study involved only 20 subjects who self-applied skin products and overall the study methodology was highly questionable