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Remarkably, TILs from 11 of 28 (39%) analyzed epithelial tumors with the 8 most frequent p53 mutants responded when co-cultured with DC pulsed with autologous mutated p53 epitopes

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The purpose here is to provide a brief overview of some of the important aspects of glutathione metabolism as part of this special issue that will provide a more comprehensive review of the state of knowledge regarding this essential molecule