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This depletion can manifest itself in ways that might include impaired nutrient absorption and assimilation, gut, lung, eye, blood, skin, and brain issues, keloid scarring, mitochondrial stress for lower energy output, DNA mutation, mass oxidation, and free radical overload (1)

Sorescu D, Weiss D, Lassegue B, Clempus RE, Szocs K, Sorescu GP, Valppu L, Quinn MT, Lambeth JD, Vega JD, Taylor WR, Griendling KK

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Western blot analysis revealed that sulforaphane alone did not obviously alter the expression of mTOR signalling components, but was highly resistant to the inhibition of phosphorylation of mTOR, p70S6K and 4E-BP1 by rotenone, in both the cerebral cortex and striatum (Fig