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34 Furthermore, a study reported that severe 25[OH]D deficiency was accompanied by an increase in TNF- in diabetic patients suffering from painful peripheral neuropathy

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The suppression of the type I IFN response by ROS is due to oxidation of cysteine 147 of murine stimulator of IFN, an ER membrane protein that mediates the IFN response after cytoplasmic DNA sensing 59,133,134