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The authors speculated that decreasing glutathione levels could be a marker for multisystem failure, which can play a significant role in the development of all kinds of chronic diseases

Although age-related eosinophilic or tigroid basophilic foci were not associated with exposure to hepatocarcinogens, in hamsters, treatment with nitrosamines or other carcinogens caused a variety of foci including basophilic foci (Frith, Ward, and Turusov 1994

By blocking both type I and type II 5-alpha reductase enzymes (compared to finasteride which only blocks type II), dutasteride provides more complete androgen suppression at the follicle level

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If clinical suspicion persists despite low or negative antibody levels, fine-needle aspiration biopsy (FNA) and cytologic examination are recommended