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The most incapacitating feature of HD is usually not the physical deficits but rather these psychosocial symptoms, which are strong predictors of the requirement for long-term care and often result in hospitalization (Loi et al

Stephan Klebe, Essen

& Bessesen, D

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In contrast, SE, AST or PHA alone or in combination, possibly by the virtue of their depicted antioxidant, anti-inflammatory and glutamate-hampering activities, were able to suppress MSG-induced elevation in ER stress markers, evidenced by marked lessening in the gene expression of PERK/CHOP/GRP78 pathway, by variable degrees, in these groups, compared to MSG-intoxicated group