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For instance, extended use of high-dose iron chelators can induce iron deficiency in the body, adversely impacting hematopoietic function, while overdosing on certain antioxidant-based inhibitors may impair coagulation function ( Figure 7 )

The apolipoprotein E4 genotype contributes to the abnormal accumulation of lipid droplets (LD) in microglia and the formation of neurotoxic LD-accumulating microglia, which are capable of directly inducing neuronal Tau phosphorylation and apoptosis, and the degree of LD accumulation is positively correlated with the severity of cognitive decline and pathology [148]

For example, peroxidases can be used for the treatment of industrial waste waters

Regulation of Nrf2 signaling pathway in heart failure: role of extracellular vesicles and non-coding RNAs

Supplementation of maturation medium with CoQ10 enhances developmental competence of ovine oocytes through improvement of mitochondrial function