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doi: 10.1016/j.immuni.2018.03.007 14 WangYCWangXYuJMaFLiZZhouYet al

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Reduced mitochondrial respiration and ATP production has been reported in Cln3 ex7/8 murine astrocytes, both under resting conditions and upon exposure to proinflammatory cytokines [46]

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We observed that a decrease in the epithelial marker cadherin 1 (CDH1) (Supplementary 5A,B) and a significant increase in mesenchymal markers like smooth muscle actin (ACTA2) and Vimentin, particularly in the TC THP1 model, indicating enhanced EMT in response to CS exposure (Supplementary Fig

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N., Paull, J

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Main Research Findings 1) Dihexa has therapeutic potential to act as a treatment for various neurological disorders related to reduced synaptic connectivity, such as Alzheimers disease

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