studied the effect of selenium supplementation on TH concentrations in ten severely deficient subjects: Se supplementation led to a significant increase in plasma selenium concentrations and GPx activity, and this was associated with a notable decrease in plasma T4 (16%) and rT3 (29%) compared to initial values
Three 30mg vials covers 90mg, sufficient for weeks 9-16 with some remaining
Heinzen EL, Pollack GM (2004) The development of morphine antinociceptive tolerance in nitric oxide synthase-deficient mice

The primary reason practitioners and their patients should be interested in using glutathione in IBS is that research suggests it is effective for helping maintain a normal inflammatory response in the gut, thus beneficially addressing IBD symptoms.* And in cases where the underlying mechanisms of the condition do overlap, a glutathione supplement could be just as beneficial in IBS as it is in IBD.* When glutathione facilitates antioxidant processes, it minimizes free radical exposure, which can trigger an inflammatory response imbalance.* If an imbalance in inflammatory response is involved in either IBS or IBD, then a glutathione supplement can be an appropriate choice.* Indeed, as far back as 1998, scientists have recognized that intestinal glutathione synthesis is impaired in patients with IBD, and this dysregulation might play a role in the etiology and progression of the condition

This recycling loop makes glutathione significantly more efficient than antioxidants that are used up after a single reaction