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The neuropsychiatric presentation of Wilsons is the first indication of disease in 4045% of patients older than 20 years of age.2,20 The youngest patient recorded with neurologic onset was 6 years old.2 The symptoms of neurologic involvement of Wilsons are usually related to dysfunction of the basal ganglia, cerebellum, and corticospinal and corticobulbar pathways

After identifying that metabolic homeostasis was restored, we used flow cytometry to quantify the influxefflux cycles

However, keep in mind that it is not necessary to escalate the dose every 4 weeks

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