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The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart

In cases of overdose, acetaminophens toxic metabolite is detoxified by glutathione, leading to rapid depletion

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3.2 Cellular and molecular effects IF enhances autophagy, an essential cellular mechanism that eliminates damaged components and maintains cellular homeostasis [24]

The source of ROS in exercising muscle is easy to conjecture, as increased O 2 demand during exercise leads to enhanced mitochondrial generation of ROS