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Underlying Health Conditions : Comorbidities such as autoimmune disorders, liver or kidney issues, or gastrointestinal diseases may slow recovery and affect how BPC-157 works

Changes in the gut microbiome during HS can also lead to reduced production of anti-inflammatory SCFAs, which in turn inhibit pattern recognition receptors (PRRs) involved in pathogen recognition and reduce the production of IL-10 and TGF- (218)