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96 LiuW.DuanX.XuL.ShangW.ZhaoJ.WangL.et al (2020)

Enhanced Absorption Protection from Degradation Increased Bioavailability Sustained Release 100% would recommend this product EM Estela M

Using vials that have been reconstituted for months likely means injecting degraded, ineffective product

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In the US, the line was further arbitrarily lowered 25% to current 150-line from [APAP]=150 at 4 hours to [APAP]=37.5 at 12 hours (purple line above) With this cutoff, failure rate of the line in acute ingestions is ~1%