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Antioxidants have been shown to inhibit the kinases such as phosphoinositide-3-kinase (PI3K) and Akt network important in oncogenic survival

Therapeutic treatment with Ibrutinib attenuates imiquimod-induced psoriasis-like inflammation in mice through downregulation of oxidative and inflammatory mediators in neutrophils and dendritic cells

It was reported that ketogenic diet reduces social deficits, repetitive behaviors, memory impairments and inflammatory markers such as TNF-, IL- 1 and IL- 6 and may be a therapeutic approach in autism spectrum disorder

Such advancements have led to our interest in using this technique to manage brain iron levels in neurological diseases, addressing a critical gap in current treatment strategies

Furthermore, upon NF-B activation, IL-10, IL-4, and IL-6 (mildly) are upregulated, while the expression of pro-inflammatory cytokines such as TNF- and IL-1 does not show a significant increase