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However, B7 also binds the CTLA4 ( CD28 ), which inhibits T cell proliferation to control rampant immune responses

While AIM2 can sense mtDNA, newly synthesized and oxidised mtDNA (ox-mtDNA) fragments are reported to activate the NLRP3 inflammasome, driving the processing of IL-1 38

Patients with compensated cirrhosis have a 4.7 times higher risk of death compared to the general population, which increases to 9.7 times higher in those with decompensated cirrhosis

doi: 10.1007/978-3-030-32300-4_27 7 SenguptaPDuttaSIrezT