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The pathophysiology of IC/BPS is poorly understood, and theories include chronic inflammation, autoimmune dysregulation, bacterial cystitis, urothelial dysfunction, deficiency of the glycosaminoglycan (GAG) barrier and urine cytotoxicity

Soni S, Torvund M, Mandal CC (2022) Omega-3 fatty acid treatment combined with chemotherapy to prevent toxicity, drug resistance, and metastasis in cancer

Short-term, they're useful

Glutathione levels decline with age and stress, reducing your body's ability to neutralize free radicals and support cellular repair

Thats because when mast cells degranulate, they release a whole host of chemical mediators including: 5,6 Histamine Cytokines Interleukins Prostaglandins Chemokines And the release of each of these pro-inflammatory mediators has a distinct impact on your body