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A recent study has demonstrated that Hinge binds to HGF with high affinity blocking its dimerization and acting as a potent inhibitor of HGF-dependent cellular activities including MDCK proliferation (Kawas et al., 2011)

doi: 10.1101/2025.05.19.654834 260 AjalaOSInnocent-UgwuDOOkechukwuPUDadaOH

The Hepatitis C virus (HCV) relies on the hosts production of phosphatidylcholine for its own replication, a mechanism driven by the viral NS3/4A protease