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Increases in blood vessel constriction by COX-2 inhibition can also lead to the hypertension and renal failure seen in some studies of non-selective and COX-2 selective NSAIDs (Conaghan 2012)

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HAYNES, R

The liver injury in Con A-induced hepatitis is associated with MNCs such as T cells, macrophages and NK cells that infiltrate into liver parenchyma

It may be that the unitary strength of glutamatergic synapses increases which in turn release more glutamate into synapses