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Chronic kidney disease and premature ageing

For the enrichment analysis at dendrites and axons, the mean TNR fluorescence intensity was calculated for all image segments in concentric circles of increasing radii

This condition ranks among the most prevalent critical illnesses, characterized by a reduced glomerular filtration rate, accumulation of nitrogenous waste products, disturbances in water and electrolyte balance, and acid-base imbalance as its primary clinical features

Major organs, including the heart, liver, spleen, lung, and kidneys, were collected for histological analysis

Serotonin promoted hepatocyte proliferation in vivo after APAP challenge As the former study showed that serotonin could promote the liver regeneration and hepatocyte proliferation after partial hepatectomy and hepatic ischemia/reperfusion injury 15,16 , we hypothesized that serotonin might also increase hepatocyte proliferation after the APAP overdose