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Major Antioxidant: Synthesis and Mechanisms of Action Timbrell, 2009, lists the three principle mechanisms of detoxification with glutathione: 1) Conjugation chemical reaction with glutathione 2) Conjugation catalysed by GSH transferase enzymes 3) Reduction by the donation of a hydrogen atom or proton as a result of oxidation of GSH

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doi: 10.1016/j.fsi.2013.01.015 36 ChambersE

Mechanisms: Immune-mediated (hypersensitivity reactions) Non-immune-mediated (related to host factors/ genetics Genetics Genetics is the study of genes and their functions and behaviors

(2019b), increased BDNF levels, greater populations of butyrate-producing bacteria, and modulation of the HPA-axis were noticed in mice administered the Bifidobacterium longum subspecies infantis strain CCFM687 and developing depressive-like behavior as a consequence of stress