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Jaspers RT, van Beek-Harmsen BJ, Blankenstein MA, Goldspink G, Huijing PA, van der Laarse WJ (2008) Hypertrophy of mature Xenopus muscle fibres in culture induced by synergy of albumin and insulin

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In addition to modulating the posttranslational modifications discussed above, improving metal delivery to SOD1 is reported to yield the greatest therapeutic benefit to multiple strains of mutant SOD1 transgenic mice to date.[ 151 , 154 , 228 ] This is consistent with data demonstrating that the toxicity of misfolded mutant SOD1 protein is more closely associated with SOD1 metal content than the total amount of mutant SOD1 protein in these mice

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The decrease of GDH1 activity limits the flow of carbon into TCA cycle (59)