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Per FDA guidance, GLP-1-based medications are generally approved for adults with a BMI over 30, or over 27 with a qualifying health condition such as type 2 diabetes, high blood pressure, or high cholesterol

While the involvement of the three latter in the regulation of plasma triglyceride hydrolysis and lipoprotein remnant uptake has been extensively studied and clearly established over years, apoC1 has long appeared as the poor relative of the family

Large-scale randomized controlled trials are essential to validate their efficacy in patients with diabetic complications, particularly for clinical assessments of diabetic retinopathy, nephropathy, and neuropathy

After applying, it will change to a pinkish red color

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