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Description

mTORC2 responds to glutamine catabolite levels to modulate the hexosamine biosynthesis enzyme GFAT1

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Front Mol Neurosci 15:829642 Eilmez OK, Aksoy F, Kalcioglu MT, Steyger PS (2024) Ototoxicity: cochleotoxicity and vestibulotoxicity

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Genetic variants that reduce UGT1A1 activity can slow glucuronidation and potentially prolong the negative effects on the endocrine system and liver

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Ritlecitinib inhibits JAK3 activity with an IC 50 of 33.1 nM [24]

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