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Description

GPX4 is a key regulator of the classical pathway of the GSHGPX4 ferroptosis pathway

We observed the catalytic GNAT domain aligned with the peptide exit tunnel and oriented with its substrate binding cavity towards the nascent polypeptide chain (Fig

Psychiatric disease ROS have been implicated in several psychiatric diseases, including depression and autism

The role of nuclear receptor NHR-64 in fat storage regulation in Caenorhabditis elegans

Schurr and Gozal demonstrated that during neuronal activation, NADHproduced via mLDHacts as an endogenous ROS scavenger, neutralizing oxidative stress induced by glutamate excitotoxicity and thereby conferring neuroprotection (Schurr and Gozal, 2011)