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RA also appeared to induce neuronal differentiation by activating ERK1/2 MAP kinase signaling pathway that phosphorylated transcription factor, CREB (cyclic AMP response element binding protein)

doi:10.3389/fnut.2021.614105

Even though levothyroxine considerably reduces lipid peroxidation, the serum MDA levels never reach the levels seen in healthy individuals (85)

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