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doi: 10.3390/ijms21030950 11 HannaMJaquaENguyenVClayJ

Elevated CSF and plasma PM levels and dried blood spot assays showing reduced PNPO enzyme activity are hallmarks of PNPO gene mutations [14]

Based on what little data exists, ipamorelin does not appear to cause adverse effects when taken on a short-term basis and the few reported side effects seem similar to those caused by other GHSs like sermorelin [6]