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Cells 8(10):1245

Policy, Culture Changes, and Institutional Responsibility: Managing Discrimination and Bias

3.4 Iron While iron deficiency (ID) has long been recognized as a driver of ineffective erythropoiesis in CKD, emerging evidence highlights that both iron deficiency and iron overload disrupt RBC longevity by promoting eryptosisthe programmed, non-hemolytic death of mature erythrocytes characterized by PS externalization, cell shrinkage, and cytoskeletal rearrangement (Lang K