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CD38 is an NAD+-consuming enzyme whose activity increases with age and chronic inflammation

Telomerase activity was quantified using the PC-3 hTERT standard curve and QuantStudio V1.3 software

These events trigger downstream signaling pathways, including AKT, Ras (rat sarcoma), and STAT3 pathways, which are required for MET biological activities (Ponzetto et al., 1994