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References Lillig, C

Glutathione and its antiaging and antimelanogenic effects Clin Cosmet Investig Dermatol

By the time of first-in-human testing, cagrilintide had demonstrated a favourable profile: strong efficacy in reducing food intake and weight, a benign safety/toxicology record, and a unique pharmacokinetic design suited for weekly dosing

It serves as a protective mechanism to regulate the passage of substances across the BBB and prevents physiologically irrelevant molecules in the peripheral circulation from entering the brain