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2023;9:eade3470

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase

One consequence of vaping-induced ventilationperfusion mismatch is an increased alveolararterial oxygen difference (AaDO2) which means oxygen is not transferring effectively and can result in hypoxemia (low blood oxygen levels) (Hopkins 2020)