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Since MTHFR deficiency is one of the treatable metabolic disorders not identified by current newborn mass screening, we should consider the possibility of MTHFR deficiency in adolescents with mental retardation who display abnormally elevated homocysteine in association with progressive neurological or psychiatric dysfunction and leukoencephalopathy

Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition

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Use R55 as the principal diagnosis