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The energy envelope model postulates that patients achieve optimal outcomes when there is a close alignment between energy expenditure and perceived available energy, resulting in enhanced physical function and reduced fatigue

The NGF/TrkA pathway participates in the induction of antioxidant responses in both the CNS and non-neural tissues (Pan and Perez-Polo, 1993, 1996

Mol Cell Biol 24:18441854 Frijhoff J, Dagnell M, Augsten M, Beltrami E, Giorgio M, Ostman A (2014) The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation