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3g, h, respectively)

HEPES-buffered (25 mM, pH 7.4) DMEM high glucose (25 mM, pH 7.4) was overlaid and plates were incubated in 37 C warm Operetta plate reader (Perkin Elmer) during the whole assay duration

7a, below) led to a significant decrease in BT549, MDA-MB-231 and Hs578t cell proliferation, which was not related to doxycycline treatment by itself (Supplementary Fig