dsip sbir topics SBIR/STTR Program Registration for Small Businesses | John McCanney posted on the topic Small Business - SBIR

The best way to stay current is to check the Defense SBIR/STTR Innovation Portal (DSIP) regularly, where all active and upcoming DoD SBIR solicitations are published in one place

PE-22-28 (Mini-Spadin) blocks TREK-1 potassium channels with ~100-fold greater potency than its parent compound, demonstrating BDNF upregulation, rapid neurogenesis within 4 days, and cognitive benefits in stroke models (Djillani et al., 2017 in Frontiers in Pharmacology)

How cagrilintide performs as a standalone treatment The 12% average weight-loss result when cagrilintide is used on its own is lower than the headline figures reported for Wegovy and Zepbound

supplied in a sterile, sealed vial for stability and consistency

Critics further worry that the regulatory change is a fait accompli, no matter the lack of evidence