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However, the most important example of drug-binding protein is represented by immunophilins (e.g., cyclophilin and FKB12) that bind with very high-affinity immunosuppressive drugs such as cyclosporine and tacrolimus (Magnani et al., 2012)

The reduced glutathione levels were measured using a GSH-Glo Assay (Promega) according to the manufacturers instructions

The satisfying reproducibility of the MPTP-induced PD symptoms, pathological changes, and mitochondrial dysfunction in primates makes it the most valuable and practical model for PD studies at present